{"id":40,"date":"2023-06-22T13:40:17","date_gmt":"2023-06-22T13:40:17","guid":{"rendered":"https:\/\/lab.chemsensim.fr\/?page_id=40"},"modified":"2026-04-02T15:36:56","modified_gmt":"2026-04-02T15:36:56","slug":"funded-projects","status":"publish","type":"page","link":"https:\/\/lab.chemsensim.fr\/index.php\/funded-projects\/","title":{"rendered":"Funded Projects"},"content":{"rendered":"\n<p><strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-accent-color\">Ongoing research projects:<\/mark>&nbsp;<\/strong><em>(*=PI S. Fiorucci ; **=PI J. Topin)<\/em>\u200b<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>INIBOR** | <\/strong>Inhibition in Olfactory Receptors<br>Funded by UniCA Idex, 2026-2027<\/li>\n\n\n\n<li><strong>PheRecIA<\/strong>* | Targeting pheromone receptors by machine learning-assisted reverse chemical ecology: a promising strategy for crop pest control.<br>Funded by ANR (ANR-25-CE20-2183), 2025-2029<\/li>\n\n\n\n<li><strong>Deciphering the molecular bases of olfactory receptor activation and inhibition.** | <\/strong>PhD thesis (Marc El Hasbany)<br>Funded by Fondation Roudnitska, 2025-2028<\/li>\n\n\n\n<li><strong>In silico reverse chemical ecology for the development of novel semiochemicals to control crop pests<\/strong>*<br>Funded by GENCI (n\u00b0AD010716722 &amp; n\u00b0A0190716857) 2025-2026<\/li>\n\n\n\n<li><strong>InvORIA* <\/strong>| Reverse chemical ecology using AI-guided high-throughput screening of insect olfactory receptors<br>Funded by France2030 &#8211; Explorae (INRAE), 2025-2029<\/li>\n\n\n\n<li><strong>ARDECO*<\/strong> | Anticipating the withdrawal of phytosanitary substances through the development of a distributed, generic and high-speed Operational Chemical Ecology infrastructure<br>Funded by FranceAgriMer, 2024-2029<\/li>\n\n\n\n<li><strong>Exploring the potential of Rab<em>X<\/em>&nbsp;inhibition to treat MAFLD<\/strong>**&nbsp;| PhD thesis (Julie Te)<br>Funded by EUR LIFE and the Academy of Excellence \u201c<em>Complexity and Diversity of Life<\/em>\u201c, 2024-2027<\/li>\n\n\n\n<li><strong>Naturalness in perfumery and its role in the world of well-being &amp; cognitive performance*<sub><sup>\/<\/sup><\/sub>**<\/strong>&nbsp;| PhD thesis (Ulrich Ambassa Meyni\u00e9)<br>Funded by ANRT (Cifre n\u00b02023\/1629), 2024-2027<\/li>\n<\/ul>\n\n\n\n<p><strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-accent-color\">Past research projects:<\/mark><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>KinetChemSen** <\/strong>| Molecular kinetics in chemical senses<br>Funded by PHC PROCOPE, 2024-2025<\/li>\n\n\n\n<li><strong>DeepGPCRLig* | GNN-NLP approach for predicting GPCR-ligand interactions and taking concentration effects into account<\/strong>*\/**<br>Funded by GENCI (n\u00b0AD010714144R1 &amp; n\u00b0A0170714144), 2024-2025<\/li>\n\n\n\n<li><strong>RevORIA<\/strong>*&nbsp;| Reverse chemical ecology using in vivo and AI approaches for understanding the evolution of host preferences in insect herbivores<br>Funded by CNRS (MITI &#8211; Prime80), 2022-2025<\/li>\n\n\n\n<li><strong>Perfume comparison by combination of machine learning and analytical chemistry*<\/strong>&nbsp;| PhD thesis (Jean-Baptiste Coffin)<br>Funded by ANRT (Cifre n\u00b02021\/1176), 2022-2025<\/li>\n\n\n\n<li><strong>Decoding Chemical Senses** <\/strong>| PhD Thesis (Maxence Lalis)<br>Funded by Fondation Roudnitska, 2021-2024<\/li>\n\n\n\n<li><strong>DeepORLig*&nbsp;<\/strong>| D\u00e9crypter le code combinatoire de l&#8217;olfaction<br>Funded by GENCI (n\u00b0AD010713580, n\u00b0A0140714144) 2022-2024<\/li>\n\n\n\n<li><a href=\"https:\/\/anr.fr\/Project-ANR-19-CE07-0044\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Chemosim*<\/strong><\/a>&nbsp;| Rational design of chemosensory compounds targeting smell, taste and emotion<br>Funded by ANR (ANR-19-CE07-0044), PRCE, 2020-2024<\/li>\n\n\n\n<li><strong>DeepLigGPCR*<\/strong>&nbsp;| Novel proteo-chemometric approaches guided by artificial intelligence methods for the rational design of novel GPCR ligands<br>Funded by CNRS (MITI &#8211; Science for AI, AI for science), 2022-2023<\/li>\n\n\n\n<li><strong>Structure-olfactive emotion relationship<\/strong>** | PhD thesis (Xhino Meleqi)<br>Funded by ANRT (Cifre n\u00b02020\/1039), 2020-2023&nbsp;<\/li>\n\n\n\n<li><strong>Perception, machine learning, data processing<\/strong>**<br>Funded by UCA Idex, Academy <em>Networks, Information and the Digital Society<\/em>, 2023<\/li>\n\n\n\n<li><a href=\"https:\/\/anr.fr\/Projet-ANR-18-CE42-0012\"><strong>OBP-Optinose<\/strong><\/a>** | Odorant Binding Proteins-based biomimetic optical nose<br>Funded by ANR (ANR-18-CE42-0012), 2018-2023<\/li>\n\n\n\n<li><strong>CroPiCro<\/strong>** | Conception Rationnelle de r\u00e9PulsIfs ciblant les R\u00e9cepteurs Olfactifs d&#8217;insecte<br>Funded by UCA Idex (Neuromod Institute), 2022<\/li>\n\n\n\n<li><strong>Molecular modeling of chemosensory receptors<\/strong>* | PhD Thesis (Jody Pacalon)<br>Funded by Fondation Roudnitska (2018-2023)<\/li>\n\n\n\n<li><strong>Following CD spectra of soluble protein during dessication<\/strong>**<br>Funded by synchrotron Aarhus (1-week beamtime), 2020 and 2022<\/li>\n\n\n\n<li><strong><a href=\"https:\/\/anr.fr\/Projet-ANR-16-CE21-0002\" target=\"_blank\" rel=\"noreferrer noopener\">Demeter*<\/a>&nbsp;<\/strong>| Bio-olfacticides : more food and less pesticides in insect control<br>Funded by ANR (ANR-16-CE21-0002), \u2018major societal challenges\u2019, 2017-2022<\/li>\n\n\n\n<li><strong>Chemokit&nbsp;*\/* <\/strong>| Chemosensory Kit for olfaction and taste training through project-based learning<br>Funded by UCA EUR (Formal, Physical &amp; Engineering Sciences) 2020-2021<\/li>\n\n\n\n<li><strong>INSECTOR<\/strong>** | Computational and experimental structure-function study of insect olfactory receptors<br>Funded by CNRS MITI, 2019-2020&nbsp;<\/li>\n\n\n\n<li><strong>Molecular basis of chemosensory perception*<\/strong>&nbsp;| PhD thesis (C\u00e9dric Bouysset)&nbsp;<br>Funded by MESR , 2018-2021.<br>Awarded by Giract &#8220;Best PhD thesis&#8221; 2022 and \u201c1st year thesis award\u201d 2018, Selected for the &#8220;Google Summer of Code&#8221; 2020, UCA Complex Days \u201cBest Poster Prize\u201d 2019, SFCi \u201cbest oral communication\u201d 2019, Gen Foundation 2019, ECRO Travel grant 2019, UCA \u201cYoung Scientist award\u201d 2019<\/li>\n\n\n\n<li><strong>A la d\u00e9couverte des sens chimiques<\/strong>**<br>Funded by UCA and Region SUD, 2020<\/li>\n\n\n\n<li><strong>NumTaste*&nbsp;<\/strong>| Designing new numerical model-guided bitter taste modulators<br>Funded by UCA Idex, Academy <em>Complex Systems<\/em>, 2020<\/li>\n\n\n\n<li><strong>Is olfactory emotion a chemical property?<\/strong>**<br>Funded by GEN foundation, 2019<\/li>\n\n\n\n<li><strong>StimOlf<\/strong>** | Stimulation Olfactive pour le traitement de l&#8217;apathie<br>Funded by UCA (AAP CSI), 2019<\/li>\n\n\n\n<li><strong>Computational Nose&nbsp;<\/strong>| A computational nose: decoding odor perception by all-atom molecular simulations of human olfactory receptors<br>Funded by PRACE 2017 &amp; GENCI 2018-2019&nbsp;<\/li>\n\n\n\n<li><strong><a rel=\"noreferrer noopener\" href=\"https:\/\/anr.fr\/Projet-ANR-15-NEUC-0005\" target=\"_blank\">NeurOlf<\/a>&nbsp;<\/strong>| Predicting odorant-dependent and independent olfactory neuron activation based on receptor dynamics<br>Funded by ANR\/NSF-NIH, Collaborative Research in Computational Neuroscience, 2015-2019<\/li>\n\n\n\n<li><strong>AI-Sweet*<\/strong>&nbsp;| Numerical models for predicting sweet taste perception.<br>Funded by UCA Idex, projet C@UCA, 2018&nbsp;<\/li>\n\n\n\n<li><strong>Molecular modeling of the sweet taste perception : structural and dynamic approches*<\/strong>&nbsp;| PhD thesis (Jean-Baptiste Ch\u00e9ron)&nbsp;<br>Funded by MESR , 2014-2017<br>Awarded by Giract \u201c1st year thesis award\u201d 2014, COST GLISTEN 2014, SFCi \u201cbest oral communication\u201d 2015, Gen Foundation 2016, ISOT 2016, UCA \u201cYoung Scientist award\u201d 2016&nbsp;<\/li>\n\n\n\n<li><strong>D\u00e9veloppement et construction de stimulants olfactifs pour traiter l\u2019apathie provoqu\u00e9e par la maladie d\u2019Alzheimer<\/strong><br>Funded by City of Nice, 2016<\/li>\n\n\n\n<li><strong>Biodiv-Nudix<\/strong>&nbsp;| Utilisation de la biodiversit\u00e9 des roses botaniques pour l\u2019\u00e9tude du r\u00f4le d\u2019une NUDIX hydrolase dans la biosynth\u00e8se du parfum<br>Funded by CNRS \u2018Mission Interdisciplinaire\u2019, PEPS interdisciplinaire EXOMOD, 2014-2015&nbsp;<\/li>\n\n\n\n<li><strong>CLIO*&nbsp;<\/strong>| Chemogenomic Links In Olfaction<br>funded by Universit\u00e9 de Nice-Sophia Antipolis, AAP CSI, 2014<\/li>\n\n\n\n<li><strong>Modeling of membrane metabolon<\/strong><br>funded by PHC AURORA, 2013-2014&nbsp;<\/li>\n\n\n\n<li><strong>Molecular modeling study of multienzymatic systems involved in flavonoid biosynthesis&nbsp;<\/strong>| &nbsp;PhD thesis (Julien Diharce)<br>Funded by MESR, 2011-2014<br>Awarded by GGMM \u201cBest PhD thesis\u201d 2017&nbsp;<\/li>\n\n\n\n<li><strong>MultiDock*&nbsp;<\/strong>| Multiresolution and multicomponent docking of large biomolecular assembly<br>funded by PHC PROCOPE, 2012-2013&nbsp;<\/li>\n\n\n\n<li><strong><a href=\"https:\/\/anr.fr\/Projet-ANR-09-BLAN-0113\" target=\"_blank\" rel=\"noreferrer noopener\">Nadyn<\/a>&nbsp;<\/strong>| DNA nanoparticles functionalized by Dynein peptide ligands for the improvement of their intracellular trafficking<br>funded by ANR programme Blanc, 2009-2012<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Ongoing research projects:&nbsp;(*=PI S. Fiorucci ; **=PI J. Topin)\u200b Past research projects:<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-40","page","type-page","status-publish"],"_links":{"self":[{"href":"https:\/\/lab.chemsensim.fr\/index.php\/wp-json\/wp\/v2\/pages\/40","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lab.chemsensim.fr\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/lab.chemsensim.fr\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/lab.chemsensim.fr\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/lab.chemsensim.fr\/index.php\/wp-json\/wp\/v2\/comments?post=40"}],"version-history":[{"count":53,"href":"https:\/\/lab.chemsensim.fr\/index.php\/wp-json\/wp\/v2\/pages\/40\/revisions"}],"predecessor-version":[{"id":891,"href":"https:\/\/lab.chemsensim.fr\/index.php\/wp-json\/wp\/v2\/pages\/40\/revisions\/891"}],"wp:attachment":[{"href":"https:\/\/lab.chemsensim.fr\/index.php\/wp-json\/wp\/v2\/media?parent=40"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}